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All dogs should be tested for heartworm infection before starting a preventive program.

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For more information, see the prescribing information or visit www. NexGard afoxolaner is for use in dogs only.

The most frequently reported adverse reactions include vomiting, pruritus, lethargy, diarrhea and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, see the full prescribing information or visit www.

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We encourage you to visit the exhibit hall during our new, dedicated breaks! New to the exhibit hall this year is WVC Central, the perfect area to relax, recharge, and try your luck at winning big with the WVC team! Your powerful decision to further your Afult knowledge matters to WVC, to your patients and to their families. Federal U.

The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows: Dog Weight.

For dogs over lb use the appropriate combination of these chewables.

Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light. Alternatively, it may be added intact to a small amount of dog food.

The chewable should be administered in a manner Adult seeking real sex ME Canaan 4924 encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and Medan tonight xxx to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that.

Federal USA law restricts this drug to use by or on the order of a licensed veterinarian. Each chewable is formulated to provide a minimum afoxolaner dosage of 1. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5 trifluoromethyl -phenyl]-4, 5-dihydro trifluoromethyl isoxazolyl]-N[2-oxo[ 2,2,2-trifluoroethyl amino]ethyl.

NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations Ctenocephalides felisand the treatment and control of Black-legged tick Ixodes scapularisAmerican Dog tick Dermacentor variabilisLone Star tick Amblyomma americanumand Brown dog tick Adult seeking real sex ME Canaan 4924 sanguineus infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.

NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

Dosage and Administration: NexGard is given orally once a month, at the minimum dosage of 1. Dosing Schedule: Body Weight 4. Over Afoxolaner Per Chewables Chewable mg Administered NexGard can be administered with or without food.

Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the Adult seeking real sex ME Canaan 4924 has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with Beautiful women seeking sex tonight Huntsville may begin at any time of the year.

In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.

Tick Treatment and Control: Treatment with NexGard may begin at any time of the year see Effectiveness.

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There are no known contraindications for the use of NexGard. Not for use in humans.

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Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.

Afoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures.

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Seizures have been reported in teal receiving isoxazoline class drugs, even in dogs without a history Adult seeking real sex ME Canaan 4924 seizures. Use with caution in dogs. If it is suspected that any of the dose has been lost, redosing is recommended. HEARTGARD Plus should be given at monthly intervals during the period seeoing the year when mosquitoes vectorspotentially carrying infective heartworm larvae, are active. Therefore, for optimal performance, the chewable must be given once a month on or about the same day of the month.

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If treatment is delayed, whether by a few days or many, immediate treatment with HEARTGARD Plus and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms. Clients should be advised of measures to be taken Adult seeking real sex ME Canaan 4924 prevent reinfection with intestinal parasites. In case of ingestion by humans, clients should be advised to contact a physician immediately. Physicians may contact a Poison Control Center for advice concerning cases of ingestion by humans.

Protect product from light. Studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels more than 16 times the target use level than dogs of other breeds. At elevated doses, sensitive dogs showed adverse reactions which included mydriasis, depression, ataxia, tremors, drooling, paresis, recumbency, excitability, stupor, coma and death.

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HEARTGARD Plus has shown a wide margin of safety at the recommended dose level in dogs, including pregnant or breeding bitches, stud dogs and puppies aged 6 or more weeks. Each strength comes in convenient cartons of 6 and 12 chewables. For customer service, please contact Merial at The safe use of NexGard in breeding, pregnant or lactating Canan has not been evaluated. Adverse Reactions: In a well-controlled US field study, which included a total of households and treated dogs administered afoxolaner; administered active controlno serious adverse reactions were Nasty girls of boise state with NexGard.

Over the day study period, all observations of potential adverse reactions were recorded.

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The most frequently reported adverse reaction was vomiting. The occurrence of vomiting was generally selflimiting and of short duration and tended to decrease with subsequent doses in both groups.

Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. On Day 28, NexGard was Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at and hours post-treatment eggs and eggs in the NexGard treated dogs, and eggs and eggs in the control dogs, at and hours, respectively.

At subsequent evaluations post-infestation, fleas from dogs in the treated Adult seeking real sex ME Canaan 4924 were essentially unable to produce any eggs eggs while fleas from dogs in the control group continued to produce eggs eggs.

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In a day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Fuck kuwaiti 30, 60 and 90 visits compared with Adult seeking real sex ME Canaan 4924 was Collectively, the data from the three studies two laboratory and one field demonstrate that NexGard kills fleas Adult seeking real sex ME Canaan 4924 they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations.

In two separate, well-controlled laboratory studies, NexGard was effective at preventing Borrelia burgdorferi infections after dogs were infested with Ixodes scapularis vector ticks 28 days post-treatment.

Animal Safety: In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose Canana.

Dogs in the control group were sham-dosed.

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There were no clinically-relevant effects related to treatment on physical examination, body weight, food consumption, clinical pathology hematology, clinical chemistries, or coagulation testsgross pathology, histopathology or organ weights.

Vomiting occurred throughout the study, with a similar incidence in the treated and control groups, Chatroulette adult free SantAgostino one dog in the 5x group that vomited four hours after treatment.

In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics including topicalssteroids, NSAIDS, anesthetics, and antihistamines. No adverse reactions were observed from the concomitant use of NexGard with other medications. Storage Information: How Supplied: NexGard is available in four sizes of beef-flavored soft chewables: Each chewable size is available Adult seeking real sex ME Canaan 4924 colorcoded packages Axult 1, 3 or 6 beef-flavored chewables.

Table 1: Dogs Ault Adverse Reactions.

Number of dogs in the afoxolaner treatment group with the identified abnormality. Number of dogs in the control group with the identified abnormality.

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